Off-contract NRL player Jamil Hopoate has been arrested on a serious drug charge.

The 26-year-old is in custody after being refused bail by police earlier today after being charged with two alleged offences following a police chase in Sydney on Tuesday.

According to News Corp Australia, Hopoate was charged with supplying a large commercial quantity of cocaine and using a vehicle to avoid apprehension.

He will spend the night behind bars and appear in Central Local Court tomorrow.