There will be a repeat of the 2019 Challenge Cup Final, as Warrington Wolves take on St Helens in the Challenge Cup Quarter Finals.
Both teams also get byes into the quarter finals.
The two remaining sixth round ties will see Castleford Tigers host Hull FC, and Wakefield Trinity against Catalans Dragons.
The winners between Castleford and Hull will take on Wigan Warriors, while either Wakefield or Catalans will face Salford Red Devils.
The final match sees Leeds Rhinos face Hull KR.
Sixth Round ties will take place on 22nd August, while the quarter-finals will take place on the weekend of 18th-20th September.
Full draw
Castleford Tigers vs. Hull FC (Sixth Round)
Wakefield Trinity vs. Catalans Dragons (Sixth Round)
Quarter Finals
Warrington Wolves vs. St Helens
Leeds Rhinos vs. Hull KR
Castleford/Hull vs. Wigan Warriors
Wakefield/Catalans vs. Salford Red Devils